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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348463
Species: Homo sapiens
RGD Object: Gene
Symbol: EP300
Name: E1A binding protein p300
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EP300increases expressionEXP 6480464CTDGlucose results in increased expression of EP300 mRNAPMID:22228707 PMID:26045780
EP300multiple interactionsEXP 6480464CTD[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]]PMID:22228707 PMID:25192544
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