Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346147
Species: Homo sapiens
RGD Object: Gene
Symbol: ALPL
Name: alkaline phosphatase, biomineralization associated
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALPLdecreases expressionISOAlpl (Rattus norvegicus)6480464CTDGlucose results in decreased expression of ALPL mRNAPMID:32643284
ALPLdecreases expressionISOAlpl (Mus musculus)6480464CTDGlucose results in decreased expression of ALPL mRNAPMID:33450223
ALPLmultiple interactionsISOAlpl (Rattus norvegicus)6480464CTDmorroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]PMID:32643284
ALPLmultiple interactionsISOAlpl (Mus musculus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]]; Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]PMID:33450223
Go Back to source page   Continue to Ontology report