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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305471
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atf6
Name: activating transcription factor 6
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf6multiple interactionsEXP 6480464CTDChlorogenic Acid inhibits the reaction [Glucose results in increased expression of ATF6 protein]; Glucose results in increased expression of and affects the localization of ATF6 protein; Metformin inhibits the reaction [Glucose results in increased expression of and affects the localization of ATF6 protein]PMID:34801538
Atf6increases expressionISOATF6 (Homo sapiens)6480464CTDGlucose deficiency results in increased expression of ATF6 proteinPMID:31022492
Atf6multiple interactionsISOATF6 (Homo sapiens)6480464CTD4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF6 protein]; ATF6 protein modified form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]]PMID:31022492
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