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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11481
Species: Mus musculus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1multiple interactionsEXP 6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of VCAM1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of VCAM1 mRNAPMID:37567420
Vcam1increases expressionISOVcam1 (Rattus norvegicus)6480464CTDGlucose results in increased expression of VCAM1 mRNAPMID:28700904
Vcam1increases expressionISOVCAM1 (Homo sapiens)6480464CTDGlucose results in increased expression of VCAM1 mRNA; Glucose results in increased expression of VCAM1 proteinPMID:15304054 PMID:16285992 PMID:21373835 PMID:21682256 PMID:25338943 PMID:31655124 PMID:38115276
Vcam1increases secretionISOVCAM1 (Homo sapiens)6480464CTDGlucose results in increased secretion of VCAM1 proteinPMID:15304054
Vcam1multiple interactionsISOVcam1 (Rattus norvegicus)6480464CTDCurcumin analog inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]PMID:28700904
Vcam1multiple interactionsISOVCAM1 (Homo sapiens)6480464CTD5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; 5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; [Glucose co-treated with Serotonin] results in increased expression of VCAM1 protein; aspalathin inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; Captopril inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; huai qi huang inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased secretion of VCAM1 protein]; nothofagin inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; Polyphenols inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Rimonabant inhibits the reaction [Glucose results in increased expression of VCAM1 protein]; sarpogrelate inhibits the reaction [[Glucose co-treated with Serotonin] results in increased expression of VCAM1 protein]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of VCAM1 protein]PMID:15304054 PMID:16285992 PMID:21373835 PMID:21682256 PMID:22785018 PMID:25338943 PMID:38115276
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