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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10862
Species: Mus musculus
RGD Object: Gene
Symbol: Ldha
Name: lactate dehydrogenase A
Acc ID: CHEBI:42758
Term: aldehydo-D-glucose
Definition: The open chain form of D-glucose.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ldhaincreases activityISOLDHA (Homo sapiens)6480464CTDGlucose results in increased activity of LDHA proteinPMID:35385194
Ldhaincreases expressionISOLDHA (Homo sapiens)6480464CTDGlucose results in increased expression of LDHA proteinPMID:27566995
Ldhamultiple interactionsISOLdha (Rattus norvegicus)6480464CTDLDHA protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]PMID:21124846
Ldhamultiple interactionsISOLDHA (Homo sapiens)6480464CTDGlucose affects the reaction [Fusaric Acid results in increased expression of LDHA mRNA]; Panax notoginseng extract inhibits the reaction [Glucose results in increased activity of LDHA protein]PMID:31654802 PMID:35385194
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