GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nat2 | increases response to substance | ISO | NAT2 (Homo sapiens) | 6480464 | CTD | NAT2 protein results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline | PMID:9150757 | Nat2 | multiple interactions | ISO | NAT2 (Homo sapiens) | 6480464 | CTD | [CYP3A7 co-treated with NAT2] results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline; [NAT2 protein results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline] which results in increased mutagenesis of APRT gene; NAT2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline | PMID:28160022 PMID:7625840 PMID:9150757 | |
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