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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:42567
Term: fisetin
Definition: A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'.
Chemical ID: MESH:C017875
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7363066480464CTDfisetin results in decreased expression of IL4 protein

PMID:16343431
multiple interactionsISORGD:7363066480464CTDfisetin inhibits the reaction [[Calcimycin co-treated with phorbol-12-myristate] results in increased expression of IL4 protein], fisetin inhibits the reaction [Calcimycin results in increased expression of IL4 mRNA]

PMID:12789233
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