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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736765
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1B1
Name: cytochrome P450 family 1 subfamily B member 1
Acc ID: CHEBI:42491
Term: flavone
Definition: The simplest member of the class of flavones that consists of 4H-chromen-4-one bearing a phenyl substituent at position 2.
Chemical ID: MESH:C043562
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1B1increases expressionEXP 6480464CTDflavone results in increased expression of CYP1B1 mRNAPMID:15890477
CYP1B1multiple interactionsEXP 6480464CTDflavone binds to and results in decreased activity of CYP1B1 proteinPMID:19563207 PMID:21053930
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