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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:42355
Term: erythromycin A
Definition: An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively.
Chemical ID: MESH:D004917
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDErythromycin inhibits the reaction [Particulate Matter results in increased expression of NQO1 mRNA], Erythromycin inhibits the reaction [Vehicle Emissions results in increased expression of NQO1 mRNA]

PMID:23291319
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.