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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732584
Species: Mus musculus
RGD Object: Gene
Symbol: Col3a1
Name: collagen, type III, alpha 1
Acc ID: CHEBI:42223
Term: emodin
Definition: A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Chemical ID: MESH:D004642
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col3a1decreases expressionISOCol3a1 (Rattus norvegicus)6480464CTDEmodin results in decreased expression of COL3A1 mRNAPMID:15288473
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