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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304916
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Optc
Name: opticin
Acc ID: CHEBI:42191
Term: ethylenediaminetetraacetic acid
Definition: A polyamino carboxylic acid that has formula C10H16N2O8.
Chemical ID: MESH:D004492
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13126316480464CTDEdetic Acid inhibits the reaction [Oxygen deficiency results in increased degradation of OPTC protein], Edetic Acid inhibits the reaction [VEGFA protein results in increased degradation of OPTC protein]

PMID:22534113
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.