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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62340
Species: Mus musculus
RGD Object: Gene
Symbol: Top2a
Name: topoisomerase (DNA) II alpha
Acc ID: CHEBI:42106
Term: L-1,4-dithiothreitol
Definition: A 1,4-dithiothreitol that has formula C4H10O2S2.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top2amultiple interactionsISOTOP2A (Homo sapiens)6480464CTDDithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]PMID:29272108
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