Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2644
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pc1
Name: glucose-6-phosphatase catalytic subunit 1
Acc ID: CHEBI:42098
Term: digoxigenin
Definition: A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.
Chemical ID: MESH:D004076
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pc1increases expressionISORGD:7360116480464CTDDigoxigenin results in increased expression of G6PC mRNA

PMID:29981919
G6pc1multiple interactionsISORGD:7360116480464CTDDigoxigenin promotes the reaction [RORC protein binds to G6PC promoter]

PMID:29981919
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.