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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3234
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oprm1
Name: opioid receptor, mu 1
Acc ID: CHEBI:41941
Term: (3,4-dihydroxyphenyl)acetic acid
Definition: A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
Chemical ID: MESH:D015102
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oprm1multiple interactionsEXP 6480464CTD[beta-funaltrexamine binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [Morphine results in increased abundance of 3, 4-Dihydroxyphenylacetic Acid]

PMID:8884884
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