Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


RGD ID: 2917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Insr
Name: insulin receptor
Acc ID: CHEBI:41941
Term: (3,4-dihydroxyphenyl)acetic acid
Definition: A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
Chemical ID: MESH:D015102
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Insrmultiple interactionsEXP 6480464CTD3, 4-Dihydroxyphenylacetic Acid inhibits the reaction [Glucose results in decreased expression of and results in decreased phosphorylation of INSR protein], 3, 4-Dihydroxyphenylacetic Acid results in increased expression of and results in increased phosphorylation of INSR protein

Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.