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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11340
Species: Mus musculus
RGD Object: Gene
Symbol: Spp1
Name: secreted phosphoprotein 1
Acc ID: CHEBI:41922
Term: diethylstilbestrol
Definition: An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Chemical ID: MESH:D004054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spp1increases expressionEXP 6480464CTDDiethylstilbestrol results in increased expression of SPP1 mRNAPMID:15289156
Spp1decreases expressionISOSPP1 (Homo sapiens)6480464CTDDiethylstilbestrol results in decreased expression of SPP1 mRNAPMID:36621641
Spp1increases expressionISOSpp1 (Rattus norvegicus)6480464CTDDiethylstilbestrol results in increased expression of SPP1 mRNAPMID:37077353
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