GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CTNNB1 | multiple interactions | EXP | | 6480464 | CTD | [Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of CTNNB1 mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CTNNB1 mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of CTNNB1 mRNA; lead nitrate inhibits the reaction [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with ascorbate-2-phosphate] results in increased expression of CTNNB1 mRNA] | PMID:28628672 PMID:35738543 | CTNNB1 | affects localization | ISO | Ctnnb1 (Rattus norvegicus) | 6480464 | CTD | Dexamethasone affects the localization of CTNNB1 protein | PMID:20501703 | CTNNB1 | decreases expression | ISO | Ctnnb1 (Mus musculus) | 6480464 | CTD | Dexamethasone results in decreased expression of CTNNB1 protein | PMID:20578217 | CTNNB1 | decreases expression | ISO | Ctnnb1 (Rattus norvegicus) | 6480464 | CTD | Dexamethasone results in decreased expression of CTNNB1 mRNA; Dexamethasone results in decreased expression of CTNNB1 protein | PMID:18467435 PMID:20501703 | CTNNB1 | multiple interactions | ISO | Ctnnb1 (Mus musculus) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of CTNNB1 protein; boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of CTNNB1 protein]; CTNNB1 protein promotes the reaction [boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of CEBPA protein]]; CTNNB1 protein promotes the reaction [boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]]; CTNNB1 protein promotes the reaction [boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARG protein]]; CTNNB1 protein promotes the reaction [sodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of CEBPA protein]]; CTNNB1 protein promotes the reaction [sodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 protein]]; CTNNB1 protein promotes the reaction [sodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARG protein]]; IWR-1 compound inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]]; Raloxifene Hydrochloride inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CTNNB1 protein]; sodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of CTNNB1 protein] | PMID:28285642 PMID:31470850 | CTNNB1 | multiple interactions | ISO | Ctnnb1 (Rattus norvegicus) | 6480464 | CTD | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of CTNNB1 protein]; Dexamethasone inhibits the reaction [2-amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine results in increased expression of CTNNB1 mRNA]; Dexamethasone results in decreased expression of and results in increased phosphorylation of CTNNB1 protein; Quercetin promotes the reaction [Dexamethasone results in decreased expression of CTNNB1 mRNA]; Quercetin promotes the reaction [Dexamethasone results in decreased expression of CTNNB1 protein] | PMID:20501703 PMID:29535048 | | ||||||||||||||||||||||
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