GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnfrsf11b | decreases expression | EXP | | 6480464 | CTD | Dexamethasone results in decreased expression of TNFRSF11B mRNA; Dexamethasone results in decreased expression of TNFRSF11B protein | PMID:27387537 PMID:28363435 | Tnfrsf11b | multiple interactions | EXP | | 6480464 | CTD | Alendronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; Alendronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]; caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]] | PMID:27387537 PMID:28363435 | Tnfrsf11b | decreases expression | ISO | Tnfrsf11b (Mus musculus) | 6480464 | CTD | Dexamethasone results in decreased expression of TNFRSF11B mRNA; Dexamethasone results in decreased expression of TNFRSF11B protein | PMID:24116280 PMID:30878453 | Tnfrsf11b | decreases expression | ISO | TNFRSF11B (Homo sapiens) | 6480464 | CTD | Dexamethasone results in decreased expression of TNFRSF11B mRNA; Dexamethasone results in decreased expression of TNFRSF11B protein | PMID:11855844 | Tnfrsf11b | increases expression | ISO | Tnfrsf11b (Mus musculus) | 6480464 | CTD | Dexamethasone results in increased expression of TNFRSF11B protein | PMID:30878453 | Tnfrsf11b | multiple interactions | ISO | Tnfrsf11b (Mus musculus) | 6480464 | CTD | [Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TNFRSF11B mRNA; EGF protein inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TNFRSF11B mRNA]; naringin inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]; naringin inhibits the reaction [Dexamethasone results in increased expression of TNFRSF11B protein]; Plant Extracts inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TNFRSF11B mRNA] | PMID:16054899 PMID:24116280 PMID:30878453 | Tnfrsf11b | multiple interactions | ISO | TNFRSF11B (Homo sapiens) | 6480464 | CTD | [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of TNFRSF11B mRNA; [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TNFRSF11B mRNA; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of TNFRSF11B mRNA; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of TNFRSF11B mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; bisphenol A promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; butylbenzyl phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; butylparaben promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; Diethylhexyl Phthalate promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA]; Pamidronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; Pamidronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; tributyltin promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; Zoledronic Acid inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; Zoledronic Acid inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein] | PMID:11855844 PMID:26424790 PMID:28628672 PMID:31016361 | | ||||||||||||||||||||||
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