Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619719
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mdh2
Name: malate dehydrogenase 2
Acc ID: CHEBI:41879
Term: dexamethasone
Definition: A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Chemical ID: MESH:D003907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdh2decreases expressionISOMdh2 (Mus musculus)6480464CTDDexamethasone results in decreased expression of MDH2 proteinPMID:33567340
Mdh2multiple interactionsISOMdh2 (Mus musculus)6480464CTD[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of MDH2 mRNAPMID:23428407
Go Back to source page   Continue to Ontology report