GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tsc22d3 | increases expression | EXP | | 6480464 | CTD | Dexamethasone results in increased expression of TSC22D3 mRNA; Dexamethasone results in increased expression of TSC22D3 protein | PMID:17998272 PMID:19997594 PMID:20671745 PMID:22733784 PMID:23183181 PMID:23946490 PMID:29624291 | Tsc22d3 | increases sumoylation | EXP | | 6480464 | CTD | Dexamethasone results in increased sumoylation of TSC22D3 protein | PMID:20671745 | Tsc22d3 | multiple interactions | EXP | | 6480464 | CTD | [benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone co-treated with Dexamethasone] results in increased ubiquitination of TSC22D3 protein; [benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; [benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]; Arsenic Trioxide promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone results in increased sumoylation of TSC22D3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; CASP8 protein promotes the reaction [Dexamethasone results in increased expression of TSC22D3 protein]; Dexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein]; Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]; lactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; Valproic Acid inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA] | PMID:17081986 PMID:20671745 PMID:23183181 PMID:23946490 | Tsc22d3 | increases expression | ISO | TSC22D3 (Homo sapiens) | 6480464 | CTD | Dexamethasone results in increased expression of TSC22D3 mRNA; Dexamethasone results in increased expression of TSC22D3 protein | PMID:17081986 PMID:19255438 PMID:22155357 PMID:23183181 PMID:25047013 PMID:25136773 PMID:28916285 PMID:31515601 | Tsc22d3 | multiple interactions | ISO | TSC22D3 (Homo sapiens) | 6480464 | CTD | 17 alpha-Hydroxyprogesterone Caproate inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; [Dexamethasone results in increased phosphorylation of and results in increased activity of NR3C1 protein] which results in increased expression of TSC22D3 mRNA; [Estradiol co-treated with Dexamethasone] inhibits the reaction [NR3C1 protein binds to TSC22D3 promoter]; [Mifepristone co-treated with Dexamethasone] results in decreased expression of TSC22D3 mRNA; [Mustard Gas results in increased alkylation of Dexamethasone] which results in increased expression of TSC22D3 mRNA; Arsenic Trioxide promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; bisphenol S affects the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein binds to TSC22D3 promoter]; ESR1 mutant form inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]; ESR1 mutant form inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]; ESR1 mutant form promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]; Fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; Fulvestrant inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]; Fulvestrant promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; Genistein inhibits the reaction [Dexamethasone promotes the reaction [NR3C1 protein binds to TSC22D3 promoter]]; Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]; liquiritigenin inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; NR3C1 mutant form inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]; TSC22D3 protein affects the reaction [Dexamethasone results in decreased expression of IL5 mRNA] | PMID:16243713 PMID:17081986 PMID:18483179 PMID:19255438 PMID:23183181 PMID:25136773 PMID:28916285 PMID:31515601 PMID:34273429 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |