GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | [[parthenolide results in decreased activity of RELA protein] which results in decreased expression of BCL2 protein] which results in increased susceptibility to Tamoxifen; [[parthenolide results in decreased activity of RELA protein] which results in increased activity of CASP8 protein] which results in increased susceptibility to Tamoxifen; RELA protein inhibits the reaction [Tamoxifen results in decreased expression of BCL2 protein]; Tamoxifen affects the localization of and results in decreased activity of RELA protein; Tamoxifen inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Tamoxifen inhibits the reaction [TNF protein results in increased activity of RELA protein] | PMID:15489888 PMID:16497877 PMID:20154269 | | ||||||||||||||||||||||
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