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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619759
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grb7
Name: growth factor receptor bound protein 7
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grb7affects expressionISOGrb7 (Mus musculus)6480464CTDTamoxifen affects the expression of GRB7 mRNAPMID:17555576
Grb7decreases response to substanceISOGRB7 (Homo sapiens)6480464CTDGRB7 protein results in decreased susceptibility to TamoxifenPMID:19075277
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