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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nans
Name: N-acetylneuraminate synthase
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nansaffects expressionISONans (Mus musculus)6480464CTDTamoxifen affects the expression of NANS mRNAPMID:17555576
Nansdecreases expressionISONANS (Homo sapiens)6480464CTDTamoxifen results in decreased expression of NANS proteinPMID:17098229
Nansmultiple interactionsISONANS (Homo sapiens)6480464CTD[Tretinoin co-treated with Tamoxifen] results in decreased expression of NANS proteinPMID:17098229
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