Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303246
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dek
Name: DEK proto-oncogene
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13490756480464CTDTamoxifen results in decreased expression of DEK mRNA, Tamoxifen results in decreased expression of DEK protein

PMID:23071688
decreases response to substanceISORGD:13490756480464CTDDEK protein results in decreased susceptibility to Tamoxifen

PMID:23071688
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.