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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11484
Species: Mus musculus
RGD Object: Gene
Symbol: Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Acc ID: CHEBI:41774
Term: tamoxifen
Definition: A stilbenoid that has formula 371.51460.
Chemical ID: MESH:D013629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vdrmultiple interactionsISOVdr (Rattus norvegicus)6480464CTDTamoxifen inhibits the reaction [Estradiol results in increased expression of VDR protein]PMID:1315250
Vdrmultiple interactionsISOVDR (Homo sapiens)6480464CTDTamoxifen inhibits the reaction [Genistein results in increased expression of VDR mRNA]; Tamoxifen inhibits the reaction [resveratrol results in increased expression of VDR mRNA]PMID:12710998
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