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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:41607
Term: crotonaldehyde
Definition: An enal consisting of propene having a formyl group at the 1-position.
Chemical ID: MESH:C012796
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2affects localizationISONFE2L2 (Homo sapiens)6480464CTD2-butenal affects the localization of NFE2L2 proteinPMID:21238556
Nfe2l2decreases response to substanceISONFE2L2 (Homo sapiens)6480464CTDNFE2L2 protein results in decreased susceptibility to 2-butenalPMID:21238556
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTDNFE2L2 protein promotes the reaction [2-butenal results in increased expression of HMOX1 protein]PMID:21238556
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