GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | EXP | | 6480464 | CTD | 4-phenylbutyric acid results in increased expression of BAX protein | PMID:33651226 | Bax | multiple interactions | EXP | | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [alpha-Chlorohydrin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Oxygen deficiency results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein] | PMID:25450231 PMID:30980806 PMID:33651226 PMID:34214594 | Bax | decreases expression | ISO | Bax (Mus musculus) | 6480464 | CTD | 4-phenylbutyric acid results in decreased expression of BAX protein | PMID:25450231 | Bax | multiple interactions | ISO | Bax (Mus musculus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-phenylbutyric acid inhibits the reaction [4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of BAX protein]] | PMID:33771661 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Ficusin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [hydroquinone results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Silver Compounds results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]; 4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]] | PMID:27816613 PMID:29306025 PMID:31364909 PMID:37148176 | |
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