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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733100
Species: Homo sapiens
RGD Object: Gene
Symbol: BCL2
Name: BCL2 apoptosis regulator
Acc ID: CHEBI:41462
Term: CARBENOXOLONE
Definition: A triterpenoid that has formula C34H50O7.
Chemical ID: MESH:D002229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCL2affects expressionEXP 6480464CTDCarbenoxolone affects the expression of BCL2 mRNAPMID:23678415
BCL2multiple interactionsEXP 6480464CTD[perfluorooctanoic acid co-treated with Carbenoxolone] results in decreased expression of BCL2 proteinPMID:32971237
BCL2multiple interactionsISOBcl2 (Rattus norvegicus)6480464CTD[[lead acetate results in increased abundance of Lead] which co-treated with Carbenoxolone] results in decreased expression of BCL2 proteinPMID:33242459
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