GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Celecoxib results in decreased expression of BAX mRNA | PMID:17342322 | Bax | increases activity | ISO | BAX (Homo sapiens) | 6480464 | CTD | Celecoxib results in increased activity of BAX protein | PMID:17952603 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Celecoxib results in increased expression of BAX protein | PMID:15688368 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [docetaxel co-treated with Celecoxib] results in increased expression of BAX protein; [tetracycline CMT-3 co-treated with Celecoxib] results in increased expression of BAX protein; BBC3 mutant form inhibits the reaction [Celecoxib results in increased activity of and results in increased localization of BAX protein]; Celecoxib results in increased activity of and results in increased localization of BAX protein | PMID:15688368 PMID:17368424 | |
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