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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345750
Species: Homo sapiens
RGD Object: Gene
Symbol: GPX2
Name: glutathione peroxidase 2
Acc ID: CHEBI:40953
Term: doramapimod
Definition: A member of the class of pyrazoles that is an immunomodulator used for treatment of rheumatoid arthritis, Crohn's disease and psoriasis.
Chemical ID: MESH:C452139
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPX2increases expressionISOGpx2 (Mus musculus)6480464CTDdoramapimod results in increased expression of GPX2 mRNAPMID:21328587
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