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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2466
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b1
Name: cytochrome P450, family 2, subfamily b, polypeptide 1
Acc ID: CHEBI:40933
Term: 5alpha-androst-16-en-3alpha-ol
Definition: A 3alpha-sterol that has formula C19H30O.
Chemical ID: MESH:C003530
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b1multiple interactionsISORGD:15583116480464CTD[1 4-bis2-3 5-dichloropyridyloxybenzene inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA [Endosulfan inhibits the reaction [androst-16-en-3-ol results in decreased activity of NR1I3 protein]] which results in increased expression of CYP2B6 mRNA

PMID:20361990
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