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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11055
Species: Mus musculus
RGD Object: Gene
Symbol: Serpine1
Name: serine (or cysteine) peptidase inhibitor, clade E, member 1
Acc ID: CHEBI:40618
Term: aminoguanidine
Definition: A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
Chemical ID: MESH:C004479
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Serpine1increases expressionISOSerpine1 (Rattus norvegicus)6480464CTDpimagedine results in increased expression of SERPINE1 mRNAPMID:18380797
Serpine1multiple interactionsISOSERPINE1 (Homo sapiens)6480464CTDpimagedine inhibits the reaction [LPA protein modified form results in increased expression of SERPINE1 protein]PMID:10856522
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