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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10357
Species: Mus musculus
RGD Object: Gene
Symbol: Chrna7
Name: cholinergic receptor, nicotinic, alpha polypeptide 7
Acc ID: CHEBI:4055
Term: cytisine
Definition: An organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking.
Chemical ID: MESH:C004712
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrna7multiple interactionsISOChrna7 (Rattus norvegicus)6480464CTDcytisine inhibits the reaction [iodo-alpha-bungarotoxin binds to CHRNA7 protein]PMID:19448648
Chrna7multiple interactionsISOCHRNA7 (Homo sapiens)6480464CTDcytisine inhibits the reaction [Bungarotoxins binds to CHRNA7 protein]PMID:10216184
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