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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708427
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d1
Name: cytochrome P450, family 2, subfamily d, polypeptide 1
Acc ID: CHEBI:4042
Term: cypermethrin
Definition: A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.
Chemical ID: MESH:C017160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDcypermethrin results in increased expression of CYP2D1 mRNA, cypermethrin results in increased expression of CYP2D1 protein

PMID:25288152
multiple interactionsEXP 6480464CTDcypermethrin promotes the reaction [cypermethrin results in increased expression of CYP2D1 mRNA], cypermethrin promotes the reaction [cypermethrin results in increased expression of CYP2D1 protein]

PMID:25288152
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