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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:4035
Term: cyhalothrin
Definition: A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.
Chemical ID: MESH:C037304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaincreases expressionEXP 6480464CTDcyhalothrin results in increased expression of RELA mRNAPMID:26645134
Relaincreases phosphorylationEXP 6480464CTDcyhalothrin results in increased phosphorylation of RELA proteinPMID:37060950
Relamultiple interactionsEXP 6480464CTDthymoquinone inhibits the reaction [cyhalothrin results in increased expression of RELA mRNA]PMID:26645134
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