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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69473
Species: Homo sapiens
RGD Object: Gene
Symbol: SREBF1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:4035
Term: cyhalothrin
Definition: A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.
Chemical ID: MESH:C037304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SREBF1multiple interactionsEXP 6480464CTD[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein]PMID:36529352
SREBF1increases expressionISOSrebf1 (Rattus norvegicus)6480464CTDcyhalothrin results in increased expression of SREBF1 mRNAPMID:27348886
SREBF1increases expressionISOSrebf1 (Mus musculus)6480464CTDcyhalothrin results in increased expression of SREBF1 mRNA; cyhalothrin results in increased expression of SREBF1 proteinPMID:36529352
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