Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347691
Species: Homo sapiens
RGD Object: Gene
Symbol: FASN
Name: fatty acid synthase
Acc ID: CHEBI:4035
Term: cyhalothrin
Definition: A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.
Chemical ID: MESH:C037304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FASNmultiple interactionsEXP 6480464CTD[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein]PMID:36529352
FASNincreases expressionISOFasn (Mus musculus)6480464CTDcyhalothrin results in increased expression of FASN mRNA; cyhalothrin results in increased expression of FASN proteinPMID:36529352
FASNincreases expressionISOFasn (Rattus norvegicus)6480464CTDcyhalothrin results in increased expression of FASN mRNA; cyhalothrin results in increased expression of FASN proteinPMID:27348886
Go Back to source page   Continue to Ontology report