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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737448
Species: Mus musculus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:4034
Term: cyfluthrin
Definition: A carboxylic ester obtained by formal condensation between 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (4-fluoro-3-phenoxyphenyl)(hydroxy)acetonitrile.
Chemical ID: MESH:C052570
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cataffects bindingISOCAT (Homo sapiens)6480464CTDcyfluthrin binds to CAT proteinPMID:32278787
Catdecreases activityISOCat (Rattus norvegicus)6480464CTDcyfluthrin results in decreased activity of CAT proteinPMID:23595963 PMID:35126122
Catdecreases activityISOCAT (Homo sapiens)6480464CTDcyfluthrin results in decreased activity of CAT proteinPMID:19961921
Catdecreases expressionISOCat (Rattus norvegicus)6480464CTDcyfluthrin results in decreased expression of CAT proteinPMID:26604153
Catdecreases expressionISOCAT (Homo sapiens)6480464CTDcyfluthrin results in decreased expression of CAT mRNAPMID:31330490
Catmultiple interactionsISOCat (Rattus norvegicus)6480464CTDbasil oil inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]PMID:23595963 PMID:35126122
Catmultiple interactionsISOCAT (Homo sapiens)6480464CTD[Melatonin co-treated with cyfluthrin] results in increased activity of CAT protein; Melatonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; N-acetylserotonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]PMID:19961921
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