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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731079
Species: Homo sapiens
RGD Object: Gene
Symbol: GRIN2B
Name: glutamate ionotropic receptor NMDA type subunit 2B
Acc ID: CHEBI:40303
Term: lovastatin
Definition: A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).
Chemical ID: MESH:D008148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRIN2Bmultiple interactionsISOGrin2b (Rattus norvegicus)6480464CTDLovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein]PMID:24718106
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