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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565476
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tuba1b
Name: tubulin, alpha 1B
Acc ID: CHEBI:40303
Term: lovastatin
Definition: A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).
Chemical ID: MESH:D008148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tuba1bdecreases expressionISOTuba1b (Mus musculus)6480464CTDLovastatin results in decreased expression of TUBA1B mRNAPMID:20493250
Tuba1bincreases expressionISOTuba1b (Mus musculus)6480464CTDLovastatin results in increased expression of TUBA1B mRNAPMID:20493250
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