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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552009
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2l1
Name: BCL2-like 1
Acc ID: CHEBI:40303
Term: lovastatin
Definition: A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).
Chemical ID: MESH:D008148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l1decreases expressionISOBcl2l1 (Rattus norvegicus)6480464CTDLovastatin results in decreased expression of BCL2L1 proteinPMID:11178870
Bcl2l1multiple interactionsISOBcl2l1 (Rattus norvegicus)6480464CTDMevalonic Acid inhibits the reaction [Lovastatin results in decreased expression of BCL2L1 protein]PMID:11178870
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