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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731006
Species: Homo sapiens
RGD Object: Gene
Symbol: PTGS2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:40287
Term: 7-NITROINDAZOLE
Definition: An indazole that has formula C7H5N3O2.
Chemical ID: MESH:C080122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS2decreases expressionISOPtgs2 (Rattus norvegicus)6480464CTD7-nitroindazole results in decreased expression of PTGS2 mRNAPMID:10691779 PMID:10894794
PTGS2multiple interactionsISOPtgs2 (Rattus norvegicus)6480464CTD7-nitroindazole affects the reaction [Sodium affects the expression of PTGS2 mRNA]; 7-nitroindazole inhibits the reaction [Sodium results in decreased expression of PTGS2 protein]PMID:10894794
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