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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730973
Species: Mus musculus
RGD Object: Gene
Symbol: Srebf2
Name: sterol regulatory element binding factor 2
Acc ID: CHEBI:40279
Term: allopurinol
Definition: A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.
Chemical ID: MESH:D000493
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf2multiple interactionsISOSrebf2 (Rattus norvegicus)6480464CTDAllopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]PMID:23647015
Srebf2multiple interactionsISOSREBF2 (Homo sapiens)6480464CTDAllopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein]PMID:23647015
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