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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10118
Species: Mus musculus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:40279
Term: allopurinol
Definition: A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.
Chemical ID: MESH:D000493
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtmultiple interactionsISOAgt (Rattus norvegicus)6480464CTDAllopurinol inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Allopurinol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]PMID:17244722 PMID:19145780
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