GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ddit3 | affects expression | EXP | | 6480464 | CTD | Cyclophosphamide affects the expression of DDIT3 mRNA | PMID:18246545 | Ddit3 | increases expression | EXP | | 6480464 | CTD | Cyclophosphamide results in increased expression of DDIT3 mRNA; Cyclophosphamide results in increased expression of DDIT3 protein | PMID:32197949 | Ddit3 | multiple interactions | EXP | | 6480464 | CTD | sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; sacubitril and valsartan sodium hydrate drug combination inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein] | PMID:32197949 | Ddit3 | decreases expression | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | Cyclophosphamide metabolite results in decreased expression of DDIT3 mRNA | PMID:24356939 | |
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