Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2295251
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c52-ps
Name: cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
Acc ID: CHEBI:4027
Term: cyclophosphamide
Definition: A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.
Chemical ID: MESH:D003520
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c52-psincreases activityISOCYP2C18 (Homo sapiens)6480464CTDCYP2C18 results in increased activity of CyclophosphamidePMID:9241661
Cyp2c52-psincreases expressionISOCyp2c11 (Rattus norvegicus)6480464CTDCyclophosphamide results in increased expression of CYP2C11 mRNAPMID:16019949
Cyp2c52-psincreases metabolic processingISOCyp2c11 (Rattus norvegicus)6480464CTDCYP2C11 results in increased metabolism of CyclophosphamidePMID:20566340
Cyp2c52-psincreases response to substanceISOCYP2C18 (Homo sapiens)6480464CTDCYP2C18 results in increased susceptibility to CyclophosphamidePMID:9766669
Cyp2c52-psmultiple interactionsISOCYP2C18 (Homo sapiens)6480464CTDPOR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]PMID:9766669
Go Back to source page   Continue to Ontology report