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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558069
Species: Mus musculus
RGD Object: Gene
Symbol: Hspa1a
Name: heat shock protein 1A
Acc ID: CHEBI:4027
Term: cyclophosphamide
Definition: A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.
Chemical ID: MESH:D003520
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa1aaffects expressionISOHspa1a (Rattus norvegicus)6480464CTDCyclophosphamide affects the expression of HSPA1A mRNAPMID:18246545
Hspa1aincreases expressionISOHSPA1A (Homo sapiens)6480464CTDCyclophosphamide results in increased expression of HSPA1A mRNA; Cyclophosphamide results in increased expression of HSPA1A proteinPMID:8917683
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