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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:4021
Term: Cyclopamine
Definition: A piperidine that has formula C27H41NO2.
Chemical ID: MESH:C000541
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:685576480464CTDcyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA], cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]]

PMID:27481074
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.