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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737517
Species: Homo sapiens
RGD Object: Gene
Symbol: STAT3
Name: signal transducer and activator of transcription 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STAT3affects expressionEXP 6480464CTDValproic Acid affects the expression of STAT3 mRNAPMID:25979313
STAT3increases expressionEXP 6480464CTDValproic Acid results in increased expression of STAT3 mRNAPMID:19101580 PMID:23179753 PMID:27188386
STAT3increases expressionISOStat3 (Mus musculus)6480464CTDValproic Acid results in increased expression of STAT3 mRNAPMID:21427059
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