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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736866
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCC3
Name: ATP binding cassette subfamily C member 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCC3affects expressionEXP 6480464CTDValproic Acid affects the expression of ABCC3 mRNAPMID:25979313
ABCC3decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of ABCC3 mRNAPMID:29501571
ABCC3decreases methylationEXP 6480464CTDValproic Acid results in decreased methylation of ABCC3 genePMID:29501571
ABCC3increases expressionEXP 6480464CTDValproic Acid results in increased expression of ABCC3 mRNA; Valproic Acid results in increased expression of ABCC3 proteinPMID:28001369 PMID:29501571
ABCC3decreases expressionISOAbcc3 (Rattus norvegicus)6480464CTDValproic Acid results in decreased expression of ABCC3 mRNAPMID:32437819
ABCC3increases expressionISOAbcc3 (Rattus norvegicus)6480464CTDValproic Acid results in increased expression of ABCC3 mRNAPMID:17381134
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